Myogenesis: A View from Drosophila
نویسندگان
چکیده
منابع مشابه
Myogenesis: A View from Drosophila
signals such as TGFb, Wnt, and Hh family members (Bate, 1993; Lawrence et al., 1995; Wu et al., 1995; Azpiazu et al., 1996; Bate and Baylies, 1996; Tajbakhsh and Mary K. Baylies,* Michael Bate,† and Mar Ruiz Gomez† *Molecular Biology Program Memorial Sloan-Kettering Cancer Center Cossu, 1997). Myogenic lineages arise from these segmental units, and genes coding for components of the Sloan Kette...
متن کاملDrosophila myogenesis
The skeletal muscle system is the largest organ in motile animals, constituting between 35 and 55% of the human body mass, and up to 75% of the body mass in flying organisms like Drosophila. The flight muscles alone in flying insects comprise up to 65% of total body mass. Not only is the musculature the largest organ system, it is also exquisitely complex, with single muscles existing in differ...
متن کاملDrosophila MEF2, a transcription factor that is essential for myogenesis.
mef2 encodes the only apparent Drosophila homolog of the vertebrate myocyte-specific enhancer factor 2 (MEF2). We show herein that the Drosophila MEF2 protein is expressed throughout the mesoderm following gastrulation. Later in embryogenesis, its expression is maintained in precursors and differentiated cells of the somatic and visceral musculature, as well as the heart. We have characterized ...
متن کاملStem cells, niches and cadherins: a view from Drosophila.
Stem cells are essential for the correct development and homeostasis of adult organisms, as well as having obvious potential therapeutic importance. Analysis of the biology of stem cells and their regulatory microenvironment in adult organs has, however, been hindered by the rarity of these cells in mature tissues and by the lack of positive markers for them. The ovary of the Drosophila melanog...
متن کاملMuscle pattern diversification in Drosophila: the story of imaginal myogenesis.
There are two phases of somatic muscle formation in Drosophila. During embryonic development, one phase of myogenesis generates larval muscle elements that mediate the relatively simple behavioural repertoire of the larva. During pupal metamorphosis, a diverse pattern of muscle fibres are assembled, and these facilitate the more elaborate behavioural patterns of the adult fly. In this review, w...
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ژورنال
عنوان ژورنال: Cell
سال: 1998
ISSN: 0092-8674
DOI: 10.1016/s0092-8674(00)81198-8